Founded by French gallerist, art dealer, and director of London's Waddington Custot Galleries, Stéphane Custot, Custot Gallery Dubai showcases some of the world's most recognised modern and contemporary artists such as Josef Albers, Jean Dubuffet, Robert Indiana, Jedd Novatt, James Rosenquist, Pierre Soulages, and Frank Stella.

The gallery represents the artists Nick Brandt, Ian Davenport, Richard Höglund, Jedd Novatt, Marc Quinn, Pablo Reinoso, Bernar Venet, Fabienne Verdier, and the Estates of Barry Flanagan and Robert Indiana.